| Genre | Shoot'em up |
| Developer(s) | Konami, Arika, SPS |
| Publisher(s) | JP/EU: Konami (Original)
JP: Sharp Corporation (X68000 version) JP/NA/PAL: Nintendo (3D Classic) JP: Hamster Corporation (PS4) |
| Composer(s) | Shigeru Fukutake, Yoshinori Sasaki |
| Series | TwinBee (series) |
| Platform(s) | Arcade, Nintendo Entertainment System, Family Computer Disk System, MSX, Virtual Console, Sharp X68000, Mobile Phone, PlayStation 4, Xbox Live Arcade, Microsoft Windows |
| Release Date | JP March 5, 1985 |
| Mode(s) | 1 player, 2 player co-op |
TwinBee (ツインビー TsuinBī) is a cartoon-themed vertical-scrolling shoot 'em up game originally released by Konami as a coin-operated video game in 1985 in Japan. It was the very first game to run on Konami's Bubble System hardware. TwinBee was ported to the Family Computer and MSX in 1986 and has been included in numerous compilations released in later years. The original arcade game was released outside Japan for the first time in the Nintendo DS compilation Konami Classics Series: Arcade Hits. A mobile phone version was released for i-mode Japan phones in 2003 with edited graphics.
Various TwinBee sequels were released for the arcade and home console markets following the original game, some which spawned audio drama and anime adaptations in Japan.